DHL Express is planning to close five domestic service centres - which employ a total of 60 people - around the UK. The company is currently involved in a formal consultation with employees at the sites in Galashiels, Scotland Aintree, Merseyside Scarborough, North Yorks Basildon, Essex and Southampton, Hants.
A spokeswoman says the move is necessary due to "current market requirements", but that DHL is looking to find suitable re-employment opportunities for staff.
She adds: "These proposals are essential for maintaining a strong operation with the right framework and which will enable DHL Express Domestic UK to keep its market-leading position in line with rapidly changing customer needs".
All the redundancy packages on offer are voluntary and it is hoped only a handful of redundancies will be necessary.
The GMB Union would not make a comment while the consultation is taking place. DHL is also planning "substantial investment in a number of facilities" but will not release further details at the moment.